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3 associated genes
4 signs/symptoms
PROTEIN INTERACTIONS: 2
1 OMIM reference -
1 associated gene
3 signs/symptoms
Well-differentiated liposarcoma
Hereditary cerebral hemorrhage with amyloidosis, Arctic type

CDK4 APP
HMGA2
MDM2


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
CDK4
MDM2
(0.56)
(0.56)
APP
APP



Citations in the biomedical literature:


Well-differentiated liposarcoma
CDK4 HMGA2 MDM2
Hereditary cerebral hemorrhage with amyloidosis, Arctic type
APP



Well-differentiated liposarcoma
Hereditary cerebral hemorrhage with amyloidosis, Arctic type

Synonym(s):
- ALT
- Atypical lipoma
- Atypical lipomatous tumor
- WDLS

Synonym(s):
- HCHWA, Arctic type

Classification (Orphanet):
- Rare oncologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
- Rare systemic or rheumatologic disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
(no data available)

Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: adult
Type of inheritance: sporadic
Epidemiological data:
(no data available)

External references:
No OMIM references
No MeSH references
External references:
1 OMIM reference -
No MeSH references

Well-differentiated liposarcoma
Hereditary cerebral hemorrhage with amyloidosis, Arctic type

Very frequent
- Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma
- Subcutaneous nodules / lipomas / tumefaction / swelling

Occasional
- Functional anomalies of the kidney and the urinary tract
- Intestinal transit disorder


Very frequent
- Autosomal dominant inheritance
- Psychic / behavioural troubles
- Psychic / psychomotor regression / dementia / intellectual decline